Why do more and more pharmaceutical factories begin to use mist shower room?

Created on:2023-11-09 14:07

the hazards of particulate matter

fine particles are very harmful to human health, because the smaller the diameter, the deeper the part of the respiratory tract. Particles with a diameter of 10 μm are usually deposited in the upper respiratory tract, and those below 2 μm can penetrate into the bronchioles and alveoli. After fine particles enter the human body to the alveoli, it directly affects the ventilation function of the lung, making the body easy to be in a state of hypoxia.

Particles with Different Sizes in Respiratory System

particle size (dp, μm) is more intuitive and easy to understand. On the one hand, the smaller the particulate matter, the deeper it enters the human respiratory system, and can even penetrate the alveoli into the human blood circulation and affect the heart, brain and other important organs, the greater the harm. As shown in the figure: coarse particulate matter PM2.5-10(2.5 <dp<10) mainly deposited in respiratory system such as throat and trachea, fine particulate matter PM1-2.5(1 <dp<2.5) can enter the lower respiratory system such as bronchi, and finer particulate matter PM0.1-1(0.1 <dp<1) can enter the lungs, ultrafine particulate matter PM0.1(dp<0.1) can penetrate the alveoli into the blood circulation system; on the other hand, the smaller the particulate matter, the larger its specific surface area, and the more toxic chemical components adsorbed on the surface.

particulate matter can cause inflammation or damage to the site or organ where it arrives to cause disease. In this process, we believe that the size of the particulate matter mainly determines "what part causes disease?", while the chemical composition determines "why causes disease?".

protective clothing different decontamination methods

fog shower room is a kind of decontamination of protective clothing, can be divided into dry fog or wet fog, according to different cleanliness level requirements, to meet different customer requirements, is different from the air shower and the shower of a decontamination equipment.

the role of mist shower chamber

, through the understanding of the hazards of particulate matter and different decontamination methods of protective clothing, we have done a good job in the weighing process of pharmaceutical enterprises to ensure that dust is not inhaled into the respiratory tract during operation, but we are in the process of taking off the protective clothing, the dust on the protective clothing may produce dust, thus inhaling into the lungs and causing harm to the operator.

The workers in the pharmaceutical and fine chemical industries producing highly active pharmaceutical ingredients (API) usually wear protective clothing when using these pharmacologically active powders. When the workers are exposed to the powders, fine dust will adhere to the work clothes. When they take off the work clothes from the controlled area to the uncontrolled area, the dust will be scattered into the space to cause pollution or breathe into the body to cause personal harm, in order to reduce the pollution of these materials from controlled areas to uncontrolled areas and cause personal hazards to staff, it is necessary to enter the fog shower chamber to dust down the harmful substances.

Composition of mist shower chamber

mist shower chamber is mainly composed of three parts: the intelligent PLC control system of the mist shower chamber atomization system.

mist shower compartment

mist shower is composed of outer plate of 304 external structure, inner plate of 304 cavity structure, single fluid nozzle, water collecting plate (including floor drain), flushable air-tight door or compression door, air supply and exhaust interface, LED waterproof lamp, etc. The double doors are interlocked, regular the fog shower room is one-way, but different functions can also be customized according to customer requirements.

atomization system

atomization system is a key part of the equipment, we all know that the size of the fog particles produced determines the decontamination ability of the equipment.

as shown in the figure: dry fog is less than 10 microns of water mist particles. It is usually formed by the effective atomization of water into fine droplets through specific technical applications. This kind of mist has a large contact area and can quickly evaporate and react with pollutants in the air. The most prominent advantage of dry fog is that it has a large contact area with air and a high evaporation rate, so that the water vapor in the dust-containing area can be saturated in a short time. Dry fog dust suppression technology is a technology that uses a high-speed rotating device to disperse water mist into tiny water droplets, and spray these water droplets into the air by wind, thereby effectively reducing the concentration of particulate matter in the air. The principle is that through the collision of water droplets and particles, the particles are attached to the surface of the water droplets, and then the dust drops by gravity. Dry fog dust suppression technology has higher efficiency and lower water consumption than traditional spray dust suppression technology.

life, we also know that if the diameter of the water droplets generated is larger than the diameter of the dust, the dust may not be wrapped and slipped directly from the side, thus the decontamination effect cannot be achieved. Only when the size of the water droplets is close to the particle size can they be wrapped. Therefore, we must ensure that the water mist generated is less than 10um, so as to effectively wrap the dust and achieve the purpose of decontamination.

Therefore, the atomizing nozzle is the technical core of the whole equipment. The atomizing nozzles used by Jie Hao are all developed and customized by himself.

intelligent PLC control system

Jie Hao's fog shower room program is designed by Siemens PLC custom programming, which can be customized according to customer needs to achieve different functions, and can also be adjusted according to the actual situation in use. Of course, for customers with limited budgets, you can also choose a simple version.

For some customers with high requirements, according to the field space or actual use, the fog shower room can also be made into an integrated decontamination equipment, which can have the functions of air shower, fog shower, water shower and so on. The pipeline system can also be equipped with air supply and exhaust systems, temperature sensors, pressure sensors, electric valves, etc.

There is no relevant national standard for the fog shower room. The above is only the company's understanding of the fog shower room after participating in a number of domestic and foreign projects. If there are any mistakes, please correct them and contribute to the development of the pharmaceutical industry. Social value.

reference standard:
of GB28670-2012 Pharmaceutical Machinery (Equipment) Implementation of Pharmaceutical Production Quality Management Standards
GB5083-1999 production equipment
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