Shanghai Jiehao's Diverse Selection of Pass Box and Professional Selection Guide

Created on:2023-11-16 14:01

 

Shanghai Jiehao's Diverse Selection of Pass Box

and Professional Selection Guide

Pass box is installed on the wall of the room partition for material transfer, with a box-type device that isolates the air in the rooms on both sides. Its purpose is to clearly distinguish between people and logistics, avoid cross-contamination, reduce the number of door opening and closing, and set up the pass box to control pollution and save energy. Biosafety laboratory is mainly used for the separation of biological risk factors, culture, detection and other experimental operations, with considerable biological hazards, so the biosafety transmission hatch is also a key protective equipment necessary for advanced biosafety laboratories.

 

Pass boxes are generally classified in different forms of disinfection, and can also be classified according to different places of use. Different types of disinfection are: ultraviolet lamp sterilization, laminar flow sterilization, pulsed xenon light sterilization, hydrogen peroxide sterilization. But from the manufacturer, more willing to classify from the applicable place. We are generally divided into low-level pass box and high-level pass box.

Low-level pass box

L01 UV lamp pass box

L02 Hepa pass box

L03 Pulsed Xenon Light Disinfection pass box

High-level transmission window

VHP ducted pass box

H01 Biosafety UV Lamp pass box

H02 biosafety hepa pass box

H03 biosafety spray pass box

H04 biosafety dunk tank

VHP pass box

VHP01 VHP Hydrogen Peroxide pass box

 

L01 UV lamp pass box

Ultraviolet lamp transmission window as the name implies is a kind of using ultraviolet lamp to achieve sterilization and disinfection of the transmission hatch. Ultraviolet radiation disinfection technology is a traditional physical disinfection method, which has the advantages of broad spectrum, high efficiency and no secondary pollution. Ultraviolet (UV) is divided into UVA(320 ~ 400nm), UVB(280 ~ 320nm) and UVC(200 ~ 280NM) according to its wavelength. UVC is easily absorbed by microorganisms and plays a role in sterilization by destroying DNA and protein structure. The commonly used ultraviolet light source is mainly 254nm low-pressure mercury lamp, low-pressure mercury lamp has the advantages of low price, mature technology, good disinfection effect, but it is harmful to the skin and eyes. (Recent studies have also shown that 222nm far-ultraviolet rays have bactericidal effects and will not cause harm to human eyes and skin. However, the inactivation effect of 254nm far-ultraviolet rays is better than 222nm far-ultraviolet rays, and 222nm far-ultraviolet rays are more likely to be interfered with by pollutants. Therefore, 254nm ultraviolet lamps are still regular used on the market at present.)

Ultraviolet lamps is generally four-sided installation, and a storage rack is placed in the middle of the transmission window to ensure all-round antivirus, and different numbers of ultraviolet lamps are set according to the size of the inner cavity. Abroad more commonly used in the form of direct external UV lamps, so that the irradiation surface is more extensive. In China, more ultraviolet lamps are built in to prevent items from being smashed, but the irradiated surface will have an impact.

 

UV LAMP OUTSET & UV LAMP EMBED

Transmission hatch also has two forms of interior and exterior. In China, the interior is generally used to ensure that the outside is flush with the wall surface. The outside is easier to clean without dead corners, but there are dead corners inside. Foreign countries more use the form of exterior door pages, so that the inner cavity is smooth and free of dead corners, and the interior is easier to clean, but because the door pages and sealing strips are exposed, dust is easy to accumulate. Any form has advantages and disadvantages, depending on the user's choice.

Embed door & outset door

L02 efficient transfer window

High-efficiency transmission windows into two categories: one is self-cleaning type, and the other is negative pressure type (also called full-in and full-out type)

Efficient delivery cabin we also callLaminar pass box, the equipment includes a fan filter unit and an ultraviolet lamp sterilization system. Fan filter unit is a kind of self-powered air supply filter device, English full name (Fan Filter Unit), referred to as FFU, modular end air supply device with filtering effect. The fan filter unit sucks in air from the top and filters it by HEPA, and the filtered clean air is evenly sent out at a speed of about 0.45 m/s 20% on the entire air outlet surface.

Self-cleaning type: the air flow in the transmission window to form an internal circulation, through the primary effect, high efficiency filter filtration and ultraviolet lamp sterilization to achieve the purpose of cleaning and disinfection, the equipment generally contains the primary effect and high efficiency.

Negative pressure type: external air intake and external air supply enter the cavity after primary effect and high efficiency filtration, disinfect by ultraviolet lamp, and then discharge into the pipeline through high efficiency. The equipment generally includes primary production and double high efficiency.

 

Self cleanning pass box & negative pressure pass box
Self cleaning pass box 
Negative pressure pass box

 

L03 Pulsed Xenon Light Disinfection Delivery Cabin

Pulsed xenon light lamp is used in the transmission window as a new type of disinfection equipment. Its principle is to use high-energy pulsed xenon light as a disinfection light source to produce strong pulsed ultraviolet light for sterilization. The advantage of pulsed xenon light is that the disinfection time is short, the spectral energy is almost unchanged during the life cycle, and the working state is less affected by changes in external conditions, thus reducing the disinfection time on the surface of the transferred items, and is suitable for places with high cleanliness requirements.a large numbertransfer the object surface disinfection of items, more efficient than the transfer window UV lamp. However, the service life of the xenon lamp is only a few hundred hours, and the disinfection effect should be tested regularly and replaced. Pulsed xenon light will produce a large amount of ozone during high-intensity irradiation. Since the transmission window is sealed during the disinfection of objects, and the transmission window door is manually opened after disinfection, the ozone in the air is relatively high. It is not clear whether it will affect the human mucosa and respiratory system.

form is the same as the general transmission window, but the light source is different.

 

High-level pass box

High-level pass box is usually used in P3 and P4 high-level biosafety laboratories. The biggest difference between it and ordinary transfer window is the sealing performance, that is, the sealing performance of the cavity and the overall sealing performance of the equipment. The verification method is generally to pump an initial pressure of -500Pa into the cavity, and the air tightness test is carried out by pressure attenuation method. The current detection standard is the requirement that the cavity pressure shall not be lower than -250Pa after 20min of pressurization in the cavity of the transfer window. The inspection standard of our factory is far higher than the industry standard. In the product suppression process, 1500Pa is usually suppressed in the cavity. Under the state of gas failure for 20 minutes, the cavity can reach the factory standard of almost no leakage.

 

P3 Biosafety Laboratory
P4 Biosafety Laboratory

The sealing form of the transmission window and door page we usually use two sealing methods: one is an inflatable seal (single or double channel can be used), and the other is a mechanical compression seal.

Inflatable airtight structure: equipment body + compressed air + inflatable sealing strip + automatic control system

Mechanical pressing structure: equipment body + connecting rod device + solid sealing strip + automatic control system

Inflatabel & Mechanical door

High-level and low-level transfer windows are almost completely different in manufacturing process. One has no requirement for sealing performance and the other needs to achieve complete sealing. This is also completely different. Of course, the use area is completely different, but the disinfection method of the equipment itself is basically the same. However, because the high-level transfer window adds VHP pipes or comes with VHP generators, each one can be sterilized with hydrogen peroxide.

Biosafety pipeline series transfer window can be sterilized in the transfer window cavity by an external VHP generator, and items that need hydrogen peroxide sterilization can also be put into the transfer window for hydrogen peroxide sterilization. Because the transfer window with VHP generator function is relatively expensive and the use position is fixed, customers will choose VHP pipeline transfer window with external sterilizer. Users can push hydrogen peroxide sterilizer to any VHP pipeline transfer window for use, saving cost and relatively flexible use.

 

H01 Biosafety UV Lamp pass box

Biosafety UV lamp delivery window includes cabinet + UV lamp sterilization system + programmable PLC control system.

Material can be stainless steel SUS304 or 316, and the equipment can be connected with the color steel plate wall or the concrete wall. The number of ultraviolet lamps can be set according to the size of the cavity and the requirements of sterilization time. Generally, there is a shelf installed inside to ensure the full range of sterilization of items.

Biosafety pass box

 

H02 biosafety efficient pass box

Biosafety high-efficiency transmission window includes cabinet + ultraviolet lamp sterilization system + high-efficiency self-purification system + programmable PLC control system.

Material can be stainless steel SUS304 or 316, and the equipment can be connected with the color steel plate wall or the concrete wall. The number of ultraviolet lamps can be set according to the size of the cavity and the requirements of sterilization time. The top cannot be installed, which will affect the air outlet.

Biosafety Hepa pass box

 

H03 biosafety spray pass box

Biosafety spray transfer hatch includes box + spray system + programmable PLC control system.

Material can be stainless steel SUS304 or 316, and the equipment can be connected with the color steel plate wall or the concrete wall. The equipment adopts a circulating spray system, pouring disinfectant into the equipment, covering the cover plate, putting the items to be disinfected into the cavity, starting the equipment, and then carrying out all-round spray disinfection on the items.

Biosafety pass box

 

H04 Biosafety dunk tank

 

Dunk tank

 

Pass box is actually various according to customer needs, including double-cavity, multi-cavity, sliding door pages, etc. The operation panel is also divided into button type, face-to-face type, touch type, etc. The control will also be different, which can realize one-way, two-way and multi-way. Although the transfer window will generally choose two doors, but there are three doors, four doors, can lead to different rooms. So the delivery hatch is actually a completely customized product.

 

 

Pass box Currentlythere is no relevant national standard, and the industry standard referred to is more than 10 years ago. The above is only the understanding of the transfer hatch after Shanghai Jiehao Company participated in a number of domestic and foreign projects. If there are any mistakes, please correct them and contribute the social value of the enterprise to the development of the pharmaceutical industry and biosafety laboratory.

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